Here are links to a couple of papers about fructose:
Fructose consumption as a risk factor for non-alcoholic fatty liver disease
http://www.ncbi.nlm.nih.gov/pubmed/18395287
Fructose overconsumption causes dyslipidemia and ectopic lipid deposition in healthy subjects with and without a family history of type 2 diabetes
http://www.ncbi.nlm.nih.gov/pubmed/19403641
1. Do we know the quantities of types of foods that Paleo people ate? If not, would this knowledge change the diet recommendations?
One thing we know is that a typical hunter-gatherer tended to eat a few leftovers in the morning, hunt/gather all day, then have a big meal at the end of the day. They were metabolically well-equipped to handle food scarcity / fasting.